The hotel offers double rooms and double or twin rooms. Double rooms have a room size of 161 sqft and accommodate 2 adults in a queen size bed. Smoking is not allowed in these rooms. Double or twin rooms have a slightly smaller room size of 129 sqft and also accommodate 2 adults in a queen size bed. Smoking is also not allowed in these rooms.

The Vicolo del Lupo Guesthouse offers a variety of leisure amenities for guests to enjoy during their stay. Firstly, guests can take advantage of the adults-only atmosphere, creating a peaceful and relaxing environment. The guesthouse also offers a garden and terrace, providing guests with the opportunity to enjoy the outdoors and soak up the sun.

In addition, the guesthouse is located near popular attractions, such as the Trevi Fountain and Spanish Steps, allowing guests to easily explore the city's famous landmarks.

Furthermore, the guesthouse offers bikes for rent, enabling guests to go on sightseeing tours or take a leisurely bike ride around the city.

Overall, guests at the Vicolo del Lupo Guesthouse can spend their time immersing themselves in the tranquil adults-only atmosphere, enjoying the outdoor spaces, exploring nearby attractions, and exploring the city by bike.