The St. Regis Kuala Lumpur offers a variety of rooms including Guest Rooms with City View, 1 King Bed Guestrooms with City View or Lake Gardens View, and suites like the Caroline Astor Suite and the John Jacob Astor Suite, both with Lake Gardens View. The rooms come with single or multiple bed options such as 1 King size bed, 2 Queen size beds, and 1 Queen size bed. Smoking is not allowed in any of the rooms at the hotel. Double rooms are available for up to 3 adults and 2 children, while suites can accommodate up to 3 adults and 2 children.

Guests at The St. Regis Kuala Lumpur can enjoy various leisure amenities during their stay. They can unwind in the hotel's outdoor swimming pool, which offers a picturesque view. For those looking to relax, the spa, steam room, sauna, and hot tub are perfect options. Families can take advantage of the Kids' Club and Kids' Meals available on-site. When it comes to dining, guests have a variety of restaurants to choose from, such as The Brasserie offering French and Korean cuisine, Sushi TAKA serving Japanese dishes, and Astor Bar providing international fare. Whether guests prefer a modern ambiance or want to enjoy a meal with a view, the hotel offers a diverse range of dining options to suit different preferences.

The hotel has several restaurants on site which offer a variety of cuisines including French, Korean, Japanese, and international dishes. The options cater to different preferences and include family-friendly and modern settings. Some of the restaurant names are The Brasserie, Sushi TAKA, Astor Bar, USHI, Crystal, and TENSHIN.